Body Composition
October 20, 2025

Muscle Asymmetry: The Hidden Factor in Strength, Resilience, and Longevity

Even small muscle imbalances can increase injury and aging risks. Explore how detecting asymmetry early supports lasting strength and resilience.

When most people think about health and performance, they think in terms of overall strength, aerobic capacity, or body composition. But there’s another, often overlooked, marker that tells us a great deal about long-term resilience: muscle asymmetry.

What Is Muscle Asymmetry

Muscle asymmetry refers to meaningful differences in muscle mass, strength, or function between the left and right sides of the body—or between opposing muscle groups. These differences are surprisingly common. Even in healthy, athletic individuals, subtle asymmetries exist. While the body is remarkably good at compensating, those compensations can carry consequences over time.

Why Asymmetry Matters

Human movement is designed around balance. Walking, running, climbing stairs, and lifting all rely on symmetrical coordination between limbs and muscle groups. When one side consistently does more work, small deviations in force or range accumulate. Over time, these hidden imbalances increase joint stress, alter gait mechanics, and accelerate wear—effects that may not be noticeable until years later.

In older adults, pronounced asymmetry is linked with reduced mobility, slower walking speed, greater fall risk, and even increased mortality. Studies show that a handgrip strength asymmetry greater than 10% predicts higher risk of functional decline, frailty, and disability even in otherwise healthy individuals. An asymmetry greater than 20% is associated with substantially increased risk of morbidity and mortality. Lower-limb differences are independently associated with impaired balance and gait speed—two of the strongest predictors of independence as we age.

In this context, symmetry isn’t about appearance—it’s a marker of structural integrity and resilience.

Hidden in Plain Sight

One of the most important aspects of muscle asymmetry is how easily it hides. Imbalances are often masked by neuromuscular efficiency—the body’s remarkable ability to compensate. A person may appear equally strong on both sides in a standard gym workout, yet precision tools like DEXA or force-plate assessments reveal measurable differences.

Why does this matter? Because asymmetries often set the stage for injuries and functional decline. Addressing them early prevents years of cumulative strain and supports efficient, sustainable movement.

How We Detect Asymmetry

Morphological Assessment (What the body looks like inside)

DEXA scanning allows us to measure regional and inter-limb differences in lean mass with remarkable precision. It detects even small variations in tissue distribution that are invisible to the eye and more accurate than field methods like bioelectrical impedance. DEXA is particularly valuable for identifying lower-limb asymmetry, which directly influences gait, balance, and fall risk.

Functional Assessment (How the body performs)

Movement and strength testing—such as Countermovement Jump Testing on force-plates—shows how asymmetries appear in real movement. Sometimes the functional deficit mirrors the lean mass difference; other times, compensatory patterns hide underlying weakness. Combining morphological and functional data provides the clearest picture of both risk and opportunity for improvement.

Why This Matters

Asymmetry doesn’t just affect athletes—it affects anyone who moves. Everyday actions like walking on uneven terrain, climbing stairs, carrying groceries, or reacting quickly to a stumble all depend on balanced strength and coordination between sides. The same principle applies to pursuits like tennis, skiing, or hiking, where quick shifts, turns, and balance recovery demand equal control from both limbs. When one side is weaker or slower to respond, small imbalances can translate into uneven joint loading and movement inefficiency.

Over time, these differences alter how you absorb force and recover from impact. Research shows that asymmetries greater than 10–15% are linked with a two- to three-fold increase in injury risk and faster progression of joint degeneration and osteoarthritis. In both active and recreational populations, side-dominant patterns are also associated with rotator cuff, hip, and lower-back injuries—often developing gradually rather than from a single event.

What Can Be Done About It

The good news: asymmetry is a modifiable risk factor. Detecting and addressing it early helps restore efficiency before it evolves into pain, instability, or long-term limitation—supporting better movement, stronger joints, and greater resilience at any age.

  • Unilateral strength training (e.g., single-leg squats, step-ups, split squats) develops the weaker side without letting the stronger limb dominate.
  • Neuromuscular control drills build coordination, balance, and proprioception to retrain symmetrical movement patterns.
  • Sport- or task-specific programming addresses repetitive stress patterns, such as a dominant swing arm in tennis or a preferred leg in soccer.
  • Routine re-testing ensures progress and prevents new imbalances from forming.

Intervention is most effective when guided by objective measurement. Combining imaging like DEXA testing and Functional Assessments takes the guesswork out of symmetry training and allows progress to be tracked with precision.

Longevity Is Built on Balance

At Evolving Health, we view muscle asymmetry as more than a biomechanical detail—it’s a marker of healthspan.  Identifying asymmetry early prevents injury and enhances performance. Correcting it preserves mobility, reduces fall risk, and supports independence.

Symmetry reflects efficiency, adaptability, and resilience—cornerstones of longevity.

References

  1. Buckinx, F. et al. Age and Ageing, 2020; 49(2): 270–276.
  2. McGrath, R. et al. Journal of the American Medical Directors Association, 2022; 23(4): 623–628.
  3. Lee, S.H. et al. Gait & Posture, 2018; 66: 220–225.
  4. Bishop, C. et al. Sports Medicine, 2022; 52(3): 531–549.
  5. Chang, A. et al. Arthritis & Rheumatism, 2007; 57(7): 1237–1243.
  6. Fousekis, K. et al. Journal of Strength and Conditioning Research, 2010; 24(8): 2284–2292.
  7. Tengku Fadilah, T.N. et al. Journal of Human Kinetics, 2021; 77: 61–72.
About the Author
About the Authors
Dr. Demetrios Sirounis, MD, FRCP

Dr. Demetrios Sirounis is a Clinical Professor in the Department of Anesthesiology, Pharmacology and Therapeutics at the University of British Columbia. He is a Fellow of the Royal College of Physicians and Surgeons of Canada and the American Society of Echocardiography and is a dually trained sub-specialist in Cardiac Anesthesiology and Critical Care Medicine. Dr. Sirounis is also an Associate Investigator at the S.H. Leong Center for Healthy Aging at the University of British Columbia.

Dr. Sirounis is a lecturer, researcher, supervisor, and Division Head of Critical Care Medicine in Vancouver. He has also served as a Duty Medical Administrator during the 2010 Olympic Winter Games Vancouver. Demetrios is a retired professional triathlete and passionate about athletics.

Jennifer Sirounis, RHN, RNCP

Jennifer is the Co-Founder of Evolving Health, a Registered Holistic Nutritionist and Registered Nutritional Consulting Practitioner.

With over 17 years of experience, she’s passionate about helping individuals unlock their vitality and reinvigorate their health. Her purpose-driven nutrition plans are designed to address each client’s immediate needs while fostering sustainable, long-term health transformations.

With an approach that values nutrition as one of the cornerstones of lasting energy and well-being, Jennifer equips her clients with the insights and tools for meaningful, life-long change.  Her expertise not only elevates healthspan and quality of life but also inspires clients to embrace a vibrant empowered future.

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